Our recent paper was highlighted on the cover of the March issue of GENETICS!

Our study exploring the genomic architecture of just a single wild yeast strain has given us an exciting peek at the remarkable contributions of SVs to intra-species genomic diversity and life history! Looking forward to future expeditions into the complex and dynamic landscapes of wild yeast genomes...


Heasley L.R.*, Argueso J.L. Bursts of genomic instability potentiate phenotypic and genomic diversification in Saccharomyces cerevisiae. Frontiers in Genetics. June. 2022. Special issue: Chromosome and Genome Biology of Fungi *corresponding author

Heasley L.R.*, Argueso J.L. Genomic characterization of a pathogenic isolate of Saccharomyces cerevisiae reveals an extensive and dynamic landscape of intra-genomic structural variation. GENETICS. PMID: 34791219. March 2022. Cover Feature. *corresponding author


Heasley L.R.*, Sampaio N.M.V., Argueso J.L. Systemic and Rapid Restructuring of the Genome: A New Perspective on Punctuated Equilibrium. Current Genetics. 2020. PMID: 33159552 *corresponding author

Sampaio N.M., Ajith V.P., Watson R.A., Heasley L.R., Chakraborty P., Rodrigues-Prause A., Malc E.P., Mieczkowski P.A., Nishant K.T., Argueso J.L. Characterization of Systemic Genomic Instability in Budding Yeast. PNAS. 2020. PMID: 33106418

Heasley L.R., Singer E., Cooperman B.J., McMurray M.A. Saccharomyces Spores are Born Prepolarized to Outgrow Away from Spore-spore Connections and Penetrate the Ascus Wall. Yeast. 2020. PMID: 33238051.

Heasley L.R., Watson R.A., & Argueso J.L. Punctuated Aneuploidization of the Budding Yeast Genome. GENETICS. 2020. PMID: 32753390 *Genetics Society of America 2020 Spotlight Featured Selection

Heasley L.R., Sampaio N.M.V., Argueso J.L., Chapter 15: Genome-Wide Analysis of Recombination in Budding Yeast. 2019. Edited by Aura Carreira and Andres Aguilera. Methods in Molecular Biology: Homologous Recombination (Springer). PMID: 32840782


Heasley L.R., DeLuca J.G., Markus S.M., Effectors of the Spindle Assembly Checkpoint are Confined Within the Nucleus of Saccharomyces cerevisiae. Biology Open. 2019. PMID:31182632


Heasley L.R., Markus S.M, DeLuca, J.G. ‘Wait Anaphase’ Signals are Not Confined to the Mitotic Spindle. MolecularBiology of the Cell. 2017. PMID:28298492. May 2017. Cover Feature.


Shaefer R., Heasley L.R., Odde D., McMurray MA. Kinetic Partitioning During de novo Septin Filament Assembly Creates a Critical G1 "Window of Opportunity" for Mutant Septin Function. Cell Cycle. 2016. PMID: 27398993

Heasley L.R. and McMurray MA. Small Molecule Perturbations of Septins. Methods in Cell Biology. Elsevier Publishing. 2016. PMID:27473917

Heasley L.R., Garcia III G., Finnigan G.C., Aggarwal A., Pearson C.G, Sterling S., Nogales E., McMurray M.A., Thorner J. Assembly Properties and Molecular Organization of Development-Specific Septins. Journal of Cell Biology. 2016. PMID:26929450

2015 and before

Heasley L.R., McMurray M.A. Roles of Septins in Prospore Membrane Morphogenesis and Spore Wall Assembly in S. cerevisisae. Molecular Biology of the Cell. 2015. PMID:26680739

Dahl K.D., Ganapathi Sankaran D., Bayless B.A., Pinter M.E., Galati D.F., Heasley L.R., Giddings Jr. T.H., Pearson C.G. A short CEP135 Splice Isoform Controls Centriole Duplication. Current Biology. 2015. PMID: 26412126

Kleczko E.K., Kim J., Keysar S.B., Heasley L.R., Eagles J.R., Simon M., Marshall M.E., Singleton K.R., Jimeno A., Tan A.C., and Heasley L.E. (2015) An inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases. PloS ONE. 2015. PMID: 25946135

Heasley L.R., Garcia 3rd G, McMurray M.A. Off-Target Effects of the Septin Drug Forchlorfenuron on Nonplant Eukaryotes. Eukaryotic Cell. 2014. F1000 Recommended PMID: 25217460

Ware K.E., Marshall M.E., Heasley L.R., Marek L., Hinz T.K., Hercule P., Helfrich B.A., and Heasley L.E. Rapidly Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in NSCLC Cell Lines Through De-repression of FGFR2 and FGFR3 Expression. PLoS ONE. 2010. PMID: 21152424